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CNN —A 62-year-old man has died months after becoming the world’s first living recipient of a genetically edited pig kidney transplant, hailed as a medical milestone. Rick Slayman received the kidney at Massachusetts General in March after he had been diagnosed with end-stage kidney disease last year. “Our family is deeply saddened about the sudden passing of our beloved Rick but take great comfort knowing he inspired so many,” a family statement said. Before Slayman’s transplant, just two transplants using pig organs had been completed – both heart transplants performed under compassionate use. EGenesis, the biotech company providing the genetically edited pig kidney, called Slayman “a true pioneer” in a statement late Saturday night.

Persons: Rick Slayman, Mr, Slayman, Slayman’s, ”, “, Rick, –, ” Slayman, Tatsuo Kawai Organizations: CNN, Massachusetts General, Massachusetts Department of Transportation, Legorreta, Procurement, Transplantation Network, Massachusetts Locations: Massachusetts, ” Massachusetts

☆ Genes known to increase the risk of Alzheimer’s may actually be an inherited form of the disorder, researchers say
▼ + stars: | 2024-05-06 | by ( Brenda Goodman | ) edition.cnn.com time to read: +10 min

Among people diagnosed with Alzheimer’s, researchers recognize familial forms of the disease and sporadic cases. This shifting appreciation of inherited risk, researchers say, is due to a better understanding of the role of a fourth gene that carries the blueprints to make a lipid-carrying protein called apolipoprotein E, known as APOE. One known as APOE2 is thought to be protective against the development of Alzheimer’s disease. They also compared people with two copies of APOE4 to people with other inherited forms of the disease — early-onset autosomal dominant Alzheimer’s disease (ADAD) and Down syndrome-associated Alzheimer’s disease (DSAD). Gene testing isn’t currently recommendedIt is also likely to change how people who carry the APOE4 gene are diagnosed and treated.

Persons: APOE4, ”, Dr, Juan Fortea, Sant, Fortea, Charles Bernick, Bernick, Alzheimer’s wasn’t, isn’t, they’re, ” Fortea, Sanjay Gupta, Reisa Sperling, “, ” Sperling, ” Dr, Sterling Johnson, Johnson Organizations: CNN, Nature, National Alzheimer’s Coordinating, Neurology, Hospital de, Cleveland Clinic Lou, Brain Health, CNN Health, Alzheimer’s Research, Brigham, Women’s, Alzheimer’s, University of Wisconsin Locations: Alzheimer’s, Spain, United States, Santa, Barcelona, Wisconsin

☆ This biotech stock specializing in targeted cancer treatments can surge 50%, Jefferies says
▼ + stars: | 2024-04-17 | by ( Pia Singh | ) www.cnbc.com time to read: +2 min

Nuvalent could be a winning biotech in the world of cancer treatments, according to Jefferies. Analyst Roger Song initiated the clinical-stage biopharmaceutical company with a buy rating and $97 price target, which implies 49.8% potential upside for shares over the next 12 months. "NUVL leverages strong expertise in structure-based chemistry and deep understanding of unmet [patient] needs to develop potentially 'best-in-class' small molecule targeted cancer therapy," Song wrote in a Wednesday note. "We think both candidates poise well in later line and have strong potential to move into frontline treatments." The company posted a fourth-quarter loss that was slightly wider than expected, at 62 cents per share.

Persons: Roger Song, Jefferies Organizations: Jefferies, U.S . Food, Drug Administration, FactSet Locations: U.S

☆ Qureight uses AI to help speed up drug development. Check out the 11-slide pitch deck it used to raise $8.5 million.
▼ + stars: | 2024-04-16 | by ( Riddhi Kanetkar | ) www.businessinsider.com time to read: +2 min

British techbio startup Qureight has secured $8.5 million in an oversubscribed Series A round. Launched in 2018, Qureight wants to simplify how pharma companies deal with the complex datasets often used during clinical trials. "For example, we can start to structure images of lungs using AI," said cofounder and CEO Muhunthan Thillai. The startup primarily works with pharmaceutical companies, including heavyweights such as AstraZeneca, as well as hospitals and clinical research organizations. Check out the 11-slide pitch deck used to secure the fresh funding.

Persons: Qureight, Muhunthan Thillai, Thillai, Hargreave Hale Organizations: pharma, Business, AstraZeneca, Hargreave Hale AIM VCT, XTX Ventures, Guinness Ventures, Playfair, Fund, Cambridge Angels Locations: Cambridge, Meltwind

☆ Pregnancy complications linked to increased risk of early death even decades later, study finds
▼ + stars: | 2024-04-15 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +8 min

CNN —Pregnancy complications, such as gestational diabetes or preeclampsia, may be linked to an elevated risk of death even decades after giving birth, according to a new study. The study, published Monday in the journal JAMA Internal Medicine, found that women who experienced major complications during pregnancy had an increased risk of early death and that risk remained elevated for more than 40 years. The data showed that more than 88,000 women had died and all five pregnancy complications were independently associated with a higher mortality risk later in life. Gestational diabetes was associated with a 52% increased risk of mortality, preterm delivery was associated with a 41% increased risk, delivering a baby with low birth weight was associated with a 30% increased risk, preeclampsia with a 13% increased risk and other hypertensive disorders with a 27% increased risk, the data showed. “We found that the increased mortality was attributable to multiple different causes of death, including heart disease, diabetes, respiratory disorders, and cancer,” he said.

Persons: Dr, Casey Crump, ” Crump, “, ”, Ashley Roman, ” Roman, Crump, Joanne Stone, Raquel, Jaime Gilinski, ” Stone, Sanjay Gupta Organizations: CNN, The University of Texas Health Science Center, Lund University, NYU Langone Health, ’, of Obstetrics, Icahn School of Medicine, CNN Health Locations: UTHealth, Houston, Malmö, Sweden, United States, Mount

☆ There’s still no standard test to detect pancreatic cancer early. Scientists are working to change that
▼ + stars: | 2024-04-08 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +11 min

But there is no standard test to detect early cases of pancreatic cancer, before cancer cells have spread and when surgery is more likely to be helpful. But many studies investigating the potential of liquid biopsy tests for the early detection of pancreatic cancer are still in the early phases. The researchers found that their liquid biopsy approach detected 93% of pancreatic cancers among the US volunteers in their study, 91% of pancreatic cancers in the South Korean cohort and 88% of pancreatic cancers in the Chinese cohort. But there is no blood test that can detect early pancreatic cancer. “Smoking is the most important avoidable risk factor for pancreatic cancer,” according to the American Cancer Society.

Persons: ”, Brian Wolpin, ” Wolpin, “ There’s, Ajay Goel, ” Goel, “, Goel, Al Neugut, Columbia University’s Herbert, Dr, Sanjay Gupta, ” Neugut, “ It’s, It’s, Wolpin Organizations: CNN, Dana, Farber Cancer Institute, US Preventive Services Task Force, American Association for Cancer Research, Hope Comprehensive Cancer Center, Molecular Diagnostics, Therapeutics, Surgeons, University of Pennsylvania, UC San Diego, Columbia, Columbia University’s Herbert Irving Comprehensive Cancer Center, Columbia University Mailman School of Public Health, CNN Health, American Cancer Society Locations: United States, City, Japan, South Korea, China, City of Hope, Hope

☆ First-degree relatives are 9 times more likely to develop a serious form of depression, study says
▼ + stars: | 2024-04-05 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +4 min

CNN —Close relatives of people with treatment-resistant depression are nine times more likely to develop depression that also does not respond to traditional treatment, a new study found. For people with treatment-resistant depression, also known as TRD, standard treatments such as psychiatric therapy and antidepressants may not work well, if at all. Being aware that treatment-resistant depression runs in families can help with early treatment options, experts say. First-degree relatives of people with TRD, which include parents, siblings and children, were nine times as likely to develop treatment-resistant depression and were at high risk of all-cause death and death by suicide compared with relatives of people without TRD, the study found. “So, this is a very welcome study indeed and goes someway to addressing the massive underrepresentation of Asian people in studies.”

Persons: CNN —, ., Ta Li, Yang Ming, ”, Andrew McIntosh, McIntosh, Justin Paget, ” Li, Li, “, ” McIntosh Organizations: Lifeline, CNN, Tung University, Centre, Clinical, Sciences, University of Edinburgh, Digital Locations: Taipei, Taiwan, Scotland, Europe, North America

☆ FDA approves new drug that may help stop and even reverse a rare, fatal condition that doctors call a ‘ticking time bomb’
▼ + stars: | 2024-03-26 | by ( Brenda Goodman | ) edition.cnn.com time to read: +15 min

These proteins cause the walls of a person’s blood vessels to keep growing and thicken over time. As the blood vessels narrow, the heart is forced to work harder to pump blood to the lungs. Treatment with a combination of drugs that dilate, or relax, blood vessels can improve this outlook, but they are not a cure. Both groups were also taking the standard medications for the condition, which help relax blood vessels to improve blood flow. But Galiatsatos said that as promising as the drug looks, there are still many unknowns, including whether the drug will benefit all PAH patients equally.

Persons: Katrina Barry, Barry, “, ”, Winrevair, Merck Winrevair, Vallerie McLaughlin, Panagis, Galiatsatos, isn’t, ” Barry, I’m, fanny, She’s, sotatercept, PAH, Sotatercept, “ There’s, Kristin Highland, Highland, ” Merck, Merck, Dr, Sanjay Gupta, Aaron Waxman, Barry’s, he’s, they’ve, Johnson –, Waxman, “ I’ve, “ It’s, who’ve Organizations: CNN, American Lung Association, US Food and Drug Administration, Merck, FDA, University of Michigan, PAH, Johns Hopkins Bayview Medical Center, New England, of Medicine, Cleveland Clinic, Institute, Clinical, CNN Health, Brigham, Women’s Hospital, Johnson Locations: PAH, American, Greece, Boston

☆ WeightWatchers CEO just sent an internal memo to employees as stock crashes, amid debt concerns, Oprah exit
▼ + stars: | 2024-03-14 | by ( Eric Rosenbaum | ) www.cnbc.com time to read: +6 min

But since then WW shares have suffered heavy selling, dropping to a new 52-week low on Thursday. The stock, due to its debt load and short interest, as well as the general anxiety about the impact of the new weight loss drugs, is subject to heightened volatility. In the memo, Sistani told employees she wanted "to take a moment to address some of the breathless media coverage." WW shares closed at $1.87 on Thursday. It noted that WW was among companies from the weight loss industry involved in the TV event.

Persons: Oprah Winfrey, Sistani, Eli Lilly, Sima Sistani, Guggenheim, Oprah, Winfrey Organizations: CNBC, Nordisk, Guggenheim Partners, Guggenheim, WeightWatchers Clinic, FDA, WeightWatchers, National Museum of, ABC

☆ Orthorexia: The clean eating disorder
▼ + stars: | 2024-03-01 | by ( Madeline Holcombe | ) edition.cnn.com time to read: +7 min

It was 20 years of an eating disorder and the anxiety and stress that comes with it culminating into one moment, he said. But clinicians are seeing a rise in orthorexia among patients, said therapist Jennifer Rollin, founder of The Eating Disorder Center in Rockville, Maryland. Orthorexia is a fixation on eating “clean,” as defined by a set of rules dependent on certain individuals and the context they live in, said Dr. Jennifer Gaudiani, an eating disorder physician and founder and medical director of the Gaudiani Clinic in Denver. When looking at therapy, check for not only an eating disorder specialist, but one with experience with orthorexia, Rollin said. People with orthorexia may find themselves with a team that includes therapists and dietitians, similar to patients in treatment for other eating disorders, Rollin said.

Persons: Jason Wood, pita, Wood, Jennifer Rollin, “, ” Rollin, Orthorexia, Jennifer Gaudiani, it’s, couldn’t, Rollin, Gaudiani, ” Gaudiani, orthorexia, ”, ” Wood, “ I’m, that’s Organizations: CNN, Disorders, Gaudiani Clinic, National Association, orthorexia Locations: Rockville , Maryland, Denver

☆ Expect AI-made prescription drugs to be ready for clinical trials in a couple of years, predicts Google DeepMind CEO
▼ + stars: | 2024-02-26 | by ( Sarah Jackson | ) www.businessinsider.com time to read: 1 min

AdvertisementOne of the foremost figures in AI thinks prescription drugs designed by AI could reach clinical testing in a few years. Google DeepMind CEO Demis Hassabis discussed his prediction on an episode of The New York Times podcast "Hard Fork" released Friday. "I think we are very close," Hassabis said when asked about whether AI was close to being capable of helping cure a major disease like Alzheimer's or a cancer. "I would say we're a couple of years away from having the first truly AI-designed drugs for a major disease, cardiovascular, cancer." This story is available exclusively to Business Insider subscribers.

Persons: Demis Hassabis, Hassabis Organizations: Google, The New York Times, Business

☆ VCs are clamoring to back 'screaming hot' startups using AI for medical records
▼ + stars: | 2024-02-21 | by ( Rebecca Torrence | ) www.businessinsider.com time to read: +7 min

Another AI medical records startup, DeepScribe, raised a $30 million Series A round in January 2022. AbridgeThe investor descent on medical-scribe startups reflects a blatant potential of automation tech to alleviate healthcare’s most critical issues. “This market is screaming hot,” said Bryan Roberts, a partner at Venrock and an investor in medical-scribe startup Suki. AdvertisementStill, as health systems increasingly adopt AI solutions to manage labor costs, these startups have room to grow into their valuations. Medical-scribe startups vying for the remaining slice of the pie are “in a pitch to the death,” Roberts said.

Persons: —, ’, Kleiner Perkins, Andreessen Horowitz, Suki, Punit Soni, Shiv Rao, ”, Bryan Roberts, ” Roberts, Annie Case, Case, Hermann, Keith Srakocic, Roberts, there’s, “ Organizations: Service, Business, Healthcare, Fund, Optum Ventures, Medical, Cathay Innovation, Microsoft, University of Pittsburgh Medical Center, University of Kansas Health, AP

☆ Healthcare startups are rushing to sell AI to hospital systems. But a new survey suggests many simply aren't ready for it.
▼ + stars: | 2024-02-20 | by ( Rebecca Torrence | ) www.businessinsider.com time to read: +4 min

As healthcare startups dive headfirst into building artificial intelligence products to sell to hospitals, a new report suggests many health systems don't yet have policies to support the tech. In a survey of 34 US health systems leaders, only 16% reported having systemwide policies for AI usage and data access. Some health system leaders said they haven't developed policies because the industry is in the early stages of AI adoption. Many health system leaders surveyed by KLAS expressed excitement about AI software for clinical documentation. Seventy percent of health system leaders surveyed by KLAS said their organizations planned to adopt AI software integrated with their EHRs.

Persons: —, hasn't, Robert Califf, KLAS, we'll, Bryan Roberts Organizations: Business, Center, Medicine, UPMC, KLAS Research, Healthcare, Food and Drug Administration, FDA, Venture, University of Pittsburgh Medical Center, University of Kansas Health, Microsoft, Industry

☆ How to fight dementia, according to neurologists
▼ + stars: | 2024-02-12 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +17 min

What about diabetes, cancer, thyroid disease, high blood pressure or heart disease? Some of the questions might seem unexpected to those who don’t write about brain health. However, my risk of developing vascular dementia, the second most common type after Alzheimer’s disease, is elevated. "Such spikes cause brain inflammation, disrupt brain metabolism and increase shrinkage of the thinking part of the brain," Isaacson said. The National Institute on Aging currently supports nearly 500 active clinical trials on Alzheimer’s disease and related dementias.

Persons: Louise Dittner, Krysta, Ryan LaMotte, It’s, ”, Natalia Rost, “, Rost, ” Rost, Richard Isaacson, ” Isaacson, mockingbird …, birthed, it’s, I’ve, Isaacson, Sandee LaMotte Organizations: CNN, Comprehensive, Massachusetts General Hospital, Harvard Medical School, American Academy of Neurology, Boca Raton, Weill Cornell Medicine, Presbyterian, Mayo Clinic, Volunteers, Alzheimer’s, National Institute on Aging, National Institutes of Health Locations: Massachusetts, Boston, neonatologists, Florida, United, New York, New York City, Nature

☆ Exclusive: Astarte Medical is shutting down. Here's why the infant tech startup decided to close its doors.
▼ + stars: | 2024-02-05 | by ( Rebecca Torrence | ) www.businessinsider.com time to read: +7 min

Tracy Warren cofounded Astarte Medical in 2016 to improve care for premature babies. Astarte, which sells software to standardize nutrition for babies in intensive care units, had raised $14 million in venture funding to date and landed contracts with four hospitals. Last year, the startup wasn't able to land as many new contracts as it hoped, with hospitals struggling to manage their slim margins. But Astarte ultimately decided not to make the promise to build AI into its tech for clinical decision-making. The startup is hoping to find a buyer by the end of the first quarter of the year.

Persons: Tracy Warren, Warren, Astarte, Tammi Jantzen, Katherine Gregory, Gregory, Warren didn't, Nenov, Jantzen, —, we've, we're, Medical's Organizations: Business, Brigham, Women's, Viking Global, Ben Franklin Technology Partners, Children's, Gillette Children's Hospital, Children's Hospital, Arkansas Children's Hospital Locations: Virginia, Minnesota, Arkansas

☆ New blood test that screens for Alzheimer’s may be a step closer to reality, study suggests
▼ + stars: | 2024-01-22 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +11 min

Alzheimer’s disease, a brain disorder that affects memory and thinking skills, is the most common type of dementia, according to the National Institutes of Health. “A blood test being negative speeds up the investigation for other causes of the symptoms and this is just as important,” Ashton said. Isaacson, who has researched blood biomarkers in people with no or minimal cognitive complaints, likened testing blood samples for signs of Alzheimer’s disease to how people undergo routine blood tests for high cholesterol. It is possible that currently available treatments for Alzheimer’s disease would work better in those diagnosed early in this way,” he said. The combination of a simple screening test with an effective treatment for Alzheimer’s disease would have a dramatic impact for individuals and for society.”

Persons: ” Nicholas Ashton, Ashton, ”, Kaj Blennow, Henrik Zetterberg, antiamyloid, immunoassay, ” Ashton, Richard Isaacson, ” Isaacson, Isaacson, ‘, “, Dr, Sanjay Gupta, David Curtis, ” Curtis Organizations: CNN, University of Gothenburg, National Institutes of Health, Quest Diagnostics, Alzheimer’s, Alzheimer’s Association, Get CNN, CNN Health, University College London, Science Media Locations: Sweden, United States, Wisconsin, Pau, Florida

☆ Here's why a top VC says healthcare investors should make growth-stage bets right now — and where he's looking for those deals
▼ + stars: | 2024-01-18 | by ( Rebecca Torrence | ) www.businessinsider.com time to read: +5 min

As a multi-stage VC fund, Lightspeed has an advantage in its exposure to both early-stage and later-stage healthcare markets, Imanbayev said. And many later-stage healthcare startups still have plenty of room to grow, he said. The first one to three years are often slow-moving for a healthcare startup, too, as it works to get its first partnerships with payers or providers, he said. But they also tend to be less risky, since later-stage startups should have revenue streams or partnerships that demonstrate their value. Lightspeed led value-based care startup Aledade's $260 million Series F in June 2023, an unusually large deal as other investors cut much smaller checks.

Persons: —, Galym, Imanbayev, I'm, There's, Farzad Mostashari, Aledade Tom Sandner, VCs, Abridge, he's, Chris Severn Organizations: Business, Lightspeed Venture Partners, Lightspeed, CVS, Health, Turquoise Health, Pharma, FDA, pharma

The full benefit for these Indian manufacturers will not be immediate, said Peter DeYoung, CEO of Piramal Pharma Solutions. Nimgaonkar said Indian CDMOs need to do more to ensure their reputation on quality standards matches Western and Chinese ones. The Indian CDMOs told Reuters that their facilities are routinely inspected by the FDA. Aragen counts seven of the 10 biggest pharma companies as clients, he said, declining to name them. "New biotechs are deciding to put eggs in both the Indian and China baskets from the start," Subramanian said.

Persons: Trump, Tommy Erdei, Ashish Nimgaonkar, Nimgaonkar, Sai, Peter DeYoung, Helen Chen, CDMOs, Piramal, DeYoung, Ramesh Subramanian, Subramanian, Maggie Fick, Andrew Silver, Michele Gershberg, Catherine Evans Organizations: Jefferies, Glyscend Therapeutics, Reuters, Sciences, Piramal Pharma, Sai Life Sciences, Western pharma, Piramal Pharma Solutions, L.E.K, Consulting, pharma, U.S . Food, Drug Administration, FDA, Thomson Locations: China, India, SHANGHAI, HYDERABAD, U.S, Shanghai, United States, London, Hyderabad

☆ F.D.A. Experts Will Vote on Safety of a Cure for Sickle Cell Disease
▼ + stars: | 2023-10-30 | by ( Gina Kolata | More About Gina Kolata | ) www.nytimes.com time to read: +4 min

An estimated 100,000 people in the United States have sickle cell disease, most of whom have African ancestry. will decide on another application for sickle cell gene therapy made by Bluebird Bio. Two other companies and an academic center, Boston Children’s Hospital, are testing their own sickle cell gene therapies. While these therapies could reduce the suffering of sickle cell patients in the United States and other wealthy countries, there is an even greater need for them in some developing countries like Nigeria. One company, Beam, is testing a way to provide gene editing that requires nothing more than a single infusion in a doctor’s office.

Persons: “, Mariah Jacqueline Scott, Scott, ”, Stephan Grupp, What’s Organizations: Institute for Clinical, CRISPR Therapeutics, Children’s Hospital of Philadelphia, Bluebird, Boston Children’s Hospital Locations: United States, Highland Park, N.J, Boston, Nigeria

☆ Pfizer to price COVID treatment Paxlovid at $1,390 per course
▼ + stars: | 2023-10-18 | by ( Michael Erman | ) www.reuters.com time to read: +3 min

The new list price, which does not include rebates and other discounts to insurers and pharmacy benefit managers, is $1,390 per course, Pfizer said in an emailed statement. The U.S. government paid around $530 per course for Paxlovid it has made available to Americans at no cost. The United States purchased around 24 million courses of the oral two-drug treatment from Pfizer, and still had a large supply, but arranged to return 7.9 million courses last week. In 2022, patients were given around 7 million courses of the drug, according to U.S. government data. Through Oct. 1, around 3.4 million courses had been administered in 2023.

Persons: Wolfgang Rattay, Paxlovid, Michael Erman, Bill Berkrot Organizations: REUTERS, Pfizer, for Clinical, Economic, United, Wall Street, Thomson Locations: U.S, United States, Maplewood , N.J

☆ Why nursing schools are turning away applicants amid a major staffing shortage
▼ + stars: | 2023-10-05 | by ( Tami Luhby | ) edition.cnn.com time to read: +8 min

CNN —At a time when registered nurses are going on strike to protest staffing shortages, thousands of applicants who want to enter or advance in the profession are being turned away from nursing schools. Nearly 78,200 qualified applications were not offered spots at nursing schools last year, according to the American Association of Colleges of Nursing, which represents schools with baccalaureate and advanced degree programs. Staffing shortages are the main reason why nursing schools are not able to accept more students who want to become registered nurses. Staffing shortages are also a major factor in the current strike by more than 75,000 unionized employees, including registered nurses, at Kaiser Permanente. The national median salary for nursing school professors with master’s degrees is just under $89,000, according to the nursing college association.

Persons: preceptors, Preceptors, ”, Judith Jarosinski, Rick Garcia, David Auerbach, Cynthia McCurren, McCurren, Jarosinski, ” McCurren, Marie Ann Marino, Thomas, “, Marino, ” Marino Organizations: CNN, American Association of Colleges of Nursing, Salisbury University’s School of Nursing, Community, Organization, Nursing, Brandeis University, Kaiser Permanente, Bureau of Labor Statistics, School of Nursing, University of Michigan, Nurse.com, Thomas Jefferson University College of Nursing, Thomas Jefferson University, US Department of Health, Human Services, Loan, Salisbury School of Nursing, Faculty Academy, Maryland Higher Education Commission, Jefferson College of Nursing, Jefferson Health, Jefferson Locations: Salisbury, Maryland, Kaiser, Flint, Philadelphia

TOKYO (AP) — Japan's health ministry has approved Leqembi, a drug for Alzheimer’s disease that was jointly developed by Japanese and U.S. pharmaceutical companies. It's the first drug for treatment of the disease in a country with a rapidly aging population. Developed by Japanese drugmaker Eisai Co. and U.S. biotechnology firm Biogen Inc., the drug's approval in Japan comes two months after it was endorsed by the U.S. Food and Drug Administration. Eisai said it will conduct a post-marketing special use survey in all patients administered the drug until enough data is collected from unspecified number of patients under Japanese health ministry procedures. Eisai is committed to delivering Leqembi to people who need it and their families “as a new treatment,” said Haruo Naito, the company’s CEO.

Persons: Fumio Kishida, Kishida, Eisai, Leqembi, ”, Haruo Naito Organizations: TOKYO, Biogen Inc, U.S . Food, Drug Administration, Kyodo Locations: Japan

A few compounds picked by AI are now in development, but those bets will take years to play out. Reuters interviews with more than a dozen pharmaceutical company executives, drug regulators, public health experts and AI firms show, however, that the technology is playing a sizeable and growing role in human drug trials. The U.S. Food and Drug Administration (FDA) said it had received about 300 applications that incorporate AI or machine learning in drug development from 2016 through 2022. Without AI, Bayer said it would have spent millions more, and taken up to nine months longer to recruit volunteers. Finding real-world patients by mining electronic patient data can be done manually, but using AI speeds up the process dramatically.

Persons: Dado Ruvic, Jeffrey Morgan, Amgen, Badhri Srinivasan, Sameer Pujari, drugmaker Bayer, Bayer, Blythe Adamson, Roche, Richard Pazdur, Gen Li, John Concato, Natalie Grover, Martin Coulter, Julie Steenhuysen, Josephine Mason, David Clarke Organizations: Pharmaceutical Research, REUTERS, Pharmaceutical, Bayer, Novartis, Deloitte, U.S . Food, Drug Administration, Reuters, World Health, Flatiron Health, FDA, European Medicines Agency, FDA's Oncology, Excellence, Medical, FDA's Center, Drug, Research, Thomson Locations: U.S, Johannesburg, Texas, Finland, United States, London, Chicago

Majority Leader Chuck Schumer said Monday that staff for the chamber’s Sergeant-at-Arms — the Senate's official clothes police — will no longer enforce a dress code on the Senate floor. “Senators are able to choose what they wear on the Senate floor. I will continue to wear a suit.”Schumer did not mention Fetterman in his statement about the dress code, which will only apply to senators, not staff. “I plan to wear a bikini tomorrow to the Senate floor,” Collins joked. “Now I can vote from the Senate floor on Mondays,” Hawley said, noting that he usually wears a suit and tie every other day.

Persons: Chuck Schumer, Pennsylvania Sen, John Fetterman, ” Schumer, Fetterman, Kansas Sen, Roger Marshall, it’s, Schumer, “, ” Marshall, Republican Sen, Susan Collins of, ” Collins, ”, “ They’re, Missouri Sen, Josh Hawley, ” Hawley, Connecticut Sen, Chris Murphy, he’s, Sergeant, ” Murphy, ” Fetterman, Kevin Freking Organizations: WASHINGTON, Senators, Kansas, Republican, Senate, Democrat, Arms, Associated Press Locations: Pennsylvania, Kansas, Susan Collins of Maine, Missouri, Connecticut

Senate Majority Leader Charles Schumer, D-N.Y., conducts a news conference after the senate luncheons in the U.S. Capitol on Wednesday, June 21, 2023. Senate Majority Leader Chuck Schumer, D-N.Y., has quietly made changes to the Senate's informal dress code to allow senators to wear whatever they want on the floor, one person with direct knowledge told NBC News. The change would let Sen. John Fetterman, D-Pa., who is often seen wearing a hoodie and baseball shorts, wear his casual attire on the Senate floor whenever he wants. Fetterman, who was elected during last year's midterm elections, was seen wearing a suit and tie during his swearing-in in January. However, the senator has worn his casual clothes after he returned to the Senate following treatment for clinical depression earlier this year.

Persons: Charles Schumer, Chuck Schumer, Sen, John Fetterman, Fetterman Organizations: U.S, Capitol, NBC News

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